The chemical imbalance theory of depression is dead - but that doesn't mean antidepressants don't work | Christopher Davey

Medicine is pragmatic. It has often established that a treatment works well before it has understood how The chemical imbalance theory of depression is well and truly dead. A paper by Joanna Moncrieff and colleagues, longtime critics of the effectiveness of antidepressants, has caused a splash. The paper provides a summary of other summaries that confirm there is no evidence to support the idea that depression is caused by disturbance of the brain's serotonin system. They have done us a favour b...